郑焙文，男，汉族，出生于1981年3月10日。毕业于中国科学院微生物研究所，专业为生物学，浙江大学传染病重症诊治全国重点实验室副研究员，博士生导师，中华医学会感染病学分会细菌真菌病学组副组长，中国疫苗行业协会细菌感染与疫苗研究专委会委员，中国微生物学会医学微生物学与免疫学专委会青委，中华预防医学会感染病防控分会青委，《中华传染病杂志》通讯编委，《中国抗生素杂志》编委，《中国感染控制杂志》青年编委等，Mil Med Res、BMC Genomics等SCI杂志编委。

研究领域：

聚焦细菌耐药、微生物基因组及微生态学研究。

主持项目：

承担国家重点研发计划项目/课题/子课题、国家自然科学基金等国家级课题8项（经费超2200万元），参与国自然科学基金国际合作重点项目、传染病重大专项子课题、“973”子课题等国家级课题10余项。

学术成果：

发表SCI论文150余篇，其中一作或通讯发表70余篇，包括Lancet Infect Dis, Intensive Care Med, Drug Resist Upda, Clin Infect Dis, Engineering等高影响力期刊，引用>4600，h-index: 32；获省部级科技成果二等奖（2项），厅级科技成果一等奖。

成果情况：

1. [论文成果] Fusion event mediated by IS903B between chromosome and plasmid in two MCR-9- and KPC-2-co-producing Klebsiella pneumoniae isolates ( 通讯作者 Drug resistance updates WOS: 77 (2024) 101139, 1-4 15.8 SCI 2024-08-16 )

2. [论文成果] A rare waterborne outbreak of Bacillus paranthracis in Shandong province, China, 2020: epidemiologic survey, genomic insights, and virulence characteristics ( 通讯作者 Emerging Microbes and Infections WOS: 卷 13, 期 12024 8.4 SCI 2024-05-07 )

3. [论文成果] Emergence of mcr-8.2-harboring hypervirulent ST412 Klebsiella pneumoniae strain from pediatric sepsis: A comparative genomic survey ( 通讯作者 Virulence WOS: 卷 14, 期 1, 页 233 - 2452023 5.5 SCI 2023-01-01 )

4. [论文成果] Biofilm formation and antibiotic sensitivity in Elizabethkingia anophelis ( 通讯作者 Frontiers in Cellular and Infection Microbiology WOS: 4.6 SCI 2022-07-28 )

5. [论文成果] Coexistence of blaIMP-4, blaNDM-1 and blaOXA-1 in blaKPC-2-producing Citrobacter freundii of clinical origin in China ( 通讯作者 Frontiers in Microbiology WOS: 4 SCI 2023-06-12 )

6. [论文成果] Complete-genome sequencing and comparative genomic characterization of blaNDM-5 carrying Citrobacter freundii isolates from a patient with multiple infections ( 通讯作者 BMC Genomics WOS: 3.5 SCI 2023-08-30 )

7. [论文成果] Bloodstream infections caused by Entero-bacteriaceae in China ( 第一位 The Lancet Infectious Diseases WOS: 36.4 SCI 2019-08-19 )

8. [论文成果] Population genomics of emerging Elizabethkingia anophelis pathogens reveals potential outbreak and rapid global dissemination ( 通讯作者 Emerging Microbes & Infections WOS: 8.4 SCI 2022-12-11 )

9. [论文成果] Small wards in the ICU: a favorable measure for controlling the transmission of carbapenem-resistant Klebsiella pneumoniae ( 通讯作者 Intensive Care Med WOS: 27.1 SCI 2022-09-21 )

10. [论文成果] Emergence and clonal dissemination of KPC-3-producing Pseudomonas aeruginosa in China with an IncP-2 megaplasmid ( 通讯作者 Annals of Clinical Microbiology and Antimicrobials WOS: 4.6 SCI 2023-04-29 )

11. [论文成果] Part of Springer Nature Annals of Clinical Microbiology and Antimicrobials ( 第一位 Environmental Pollution WOS: 7.6 SCI 2021-01-08 )

12. [论文成果] Stool Samples of Acute Diarrhea Inpatients as a Reservoir of ST11 Hypervirulent KPC-2-Producing Klebsiella pneumoniae ( 第一位 mSystems WOS: 5 SCI 2020-06-23 )

13. [论文成果] Occurrence and Genomic Characterization of Two MCR-1-Producing Escherichia coli Isolates from the Same Mink Farmer ( 第一位 mSphere WOS: 3.7 SCI 2019-11-06 )

14. [论文成果] Emergence and Comparative Genomics Analysis of Extended-Spectrum-β-Lactamase-Producing Escherichia coli Carrying mcr-1 in Fennec Fox Imported from Sudan to China ( 通讯作者 mSphere WOS: 3.7 SCI 2019-11-20 )

15. [论文成果] Coexistence of blaIMP-4 and blaSFO-1 in an IncHI5B plasmid harbored by tigecycline-non-susceptible Klebsiella variicola strain ( 通讯作者 Annals of Clinical Microbiology and Antimicrobials WOS: 4.6 SCI 2024-03-06 )

16. [论文成果] Dynamic cytokine profiles of bloodstream infection caused by Klebsiella pneumoniae in China ( 通讯作者 Annals of Clinical Microbiology and Antimicrobials WOS: 4.6 SCI 2024-08-24 )

17. [论文成果] Emergence of KPC-2-Producing Raoultella ornithinolytica Isolated from a Hospital Wastewater Treatment Plant ( 通讯作者 Antimicrobial Agents and Chemotherapy WOS: 4.1 SCI 2020-01-27 )

18. [论文成果] Characterizations of heavy metal contamination, microbial community, and resistance genes in a tailing of the largest copper mine in China ( 通讯作者 Environmental Pollution WOS: 7.6 SCI 2021-07-01 )

19. [论文成果] Detection and characterization of ESBL-producing Escherichia coli expressing mcr-1 from dairy cows in China ( 第一位 Journal of Antimicrobial Chemotherapy WOS: 3.9 SCI 2019-02-01 )

20. [论文成果] Emergence of plasmid-borne tet(X4) resistance gene in clinical isolate of eravacycline- and omadacycline-resistant Klebsiella pneumoniae ST485 ( 通讯作者 Microbiology Spectrum WOS: 3.7 SCI 2024-09-03 )

21. [论文成果] Antagonistic effect between tigecycline and meropenem: successful management of KPC-producing Klebsiella pneumoniae infection ( 通讯作者 Infection WOS: 5.4 SCI 2019-02-07 )

22. [论文成果] Emergence and Characterization of a Novel IncP-6 Plasmid Harboring bla KPC-2 and qnrS2 Genes in Aeromonas taiwanensis Isolates ( 通讯作者 frontiers in Microbiology WOS: 4 SCI 2019-09-12 )

23. [论文成果] Whole Genome Sequencing of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Isolated From a Wastewater Treatment Plant in China ( 通讯作者 frontiers in Microbiology WOS: 4 SCI 2019-08-02 )

24. [论文成果] Emergence of NDM-1- and CTX-M-3-Producing Raoultella ornithinolytica in Human Gut Microbiota ( 通讯作者 frontiers in Microbiology WOS: 4 SCI 2019-11-22 )

25. [论文成果] First report of Klebsiella pneumoniae co-producing OXA-181, CTX-M-55, and MCR-8 isolated from the patient with bacteremia ( 通讯作者 frontiers in Microbiology WOS: 4 SCI 2022-10-14 )

26. [论文成果] Confirmation of the Need for Reclassification of Neisseria mucosa and Neisseria sicca Using Average Nucleotide Identity Blast and Phylogenetic Analysis of Whole-Genome Sequencing: Hinted ( 通讯作者 frontiers in Microbiology WOS: 4 SCI 2022-02-21 )

27. [论文成果] Detection of IMP-4 and SFO-1 co-producing ST51 Enterobacter hormaechei clinical isolates ( 通讯作者 Frontiers in Cellular and Infection Microbiology WOS: 4.6 SCI 2022-10-27 )

28. [论文成果] Genomic Characterization of Two Escherichia fergusonii Isolates Harboring mcr-1 Gene From Farm Environment ( 通讯作者 Frontiers in Cellular and Infection Microbiology WOS: 4.6 SCI 2022-05-26 )

29. [论文成果] Emergence of Neonatal Sepsis Caused by MCR-9- and NDM-1-Co-Producing Enterobacter hormaechei in China ( 通讯作者 Frontiers in Cellular and Infection Microbiology WOS: 4.6 SCI 2022-05-06 )

30. [论文成果] Flavorubredoxin, a Candidate Trigger Related to Thrombotic Thrombocytopenic Purpura: Screening of the Complete Genome of a Salmonella enterica Serovar Typhimurium Isolate From an AIDS Case ( 通讯作者 Frontiers in Cellular and Infection Microbiology WOS: 4.6 SCI 2022-06-10 )

31. [论文成果] Genomic characterisation of a colistin-resistant Klebsiella pneumoniae ST11 strain co-producing KPC-2, FloR, CTX-M-55, SHV-12, FosA and RmtB causing a lethal infection ( 通讯作者 sdiit00811 WOS: 3.7 SCI 2019-12-19 )

32. [论文成果] Complete genome sequence of an IMP-8, CTX-M-14, CTX-M-3 and QnrS1 co-producing Enterobacter asburiae isolate from a patient with wound infection ( 通讯作者 Journal of Global Antimicrobial Resistance WOS: 3.7 SCI 2019-09-18 )

33. [论文成果] Intestinal colonization with ESBL-producing Klebsiella pneumoniae in healthy rural villager: A genomic surveillance study in China, 2015-2017 ( 通讯作者 Frontiers in Public Health WOS: 3 SCI 2022-12-15 )

34. [论文成果] Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant ( 通讯作者 Infection and Drug Resistance WOS: 2.9 SCI 2019-09-06 )

35. [论文成果] Complete-Genome Sequencing and Comparative Genomic Characterization of an IMP-4 Producing Citrobacter freundii Isolate from Patient with Diarrhea ( 通讯作者 Infection and Drug Resistance WOS: 2.9 SCI 2020-04-14 )

36. [论文成果] Carbapenem-Resistant Enterobacter hormaechei ST1103 with IMP-26 Carbapenemase and ESBL Gene bla SHV-178 ( 通讯作者 Infection and Drug Resistance WOS: 2.9 SCI 2020-02-20 )

37. [论文成果] Genomic and Phenotypic Diversity of Listeria monocytogenes Causing Pregnancy-Associated Listeriosis from Zhejiang Province, China, 2016-2018 ( 通讯作者 Infection and Drug Resistance WOS: 2.9 SCI 2020-04-23 )